Fig. 3: Comparison of behavioral phenotypes in fathers and male offspring.

Note, that offspring are plotted against diet composition of fathers. Time and activity in different zones of an elevated plus maze, assayed at 15 weeks of age. a, d percentage of time spent in closed arms, b, e percentage of time spent in center zone, c, f number of entries into center zone. An effect of dietary macronutrient content on the outcome of interest was inferred when the non-null statistical model (i.e., that fitting an effect of diet) had an Akaike Information Criterion (AIC) more than two points lower than the null model (i.e., △AIC < -2). a F0 Closed arm % △AIC = -2.19, n = 60, b F0 Centre % △AIC = -35.33, n = 60, c F0 Centre bouts △AIC = -9.87, n = 60, d F1 Closed arm % △AIC = -5.24, n = 50, e F1 Centre % △AIC = -5.53, n = 50, f F1 Centre bouts △AIC = -7.33, n = 50. Full model coefficients are given in Supp Table 2. Source data for fathers (a–c) are provided in Source Data File 1, and that for male offspring (d–f) in Source Data File 3. Created with BioRender.com.