Fig. 1: Single-cell expression profiling of human HNSCC. | Nature Communications

Fig. 1: Single-cell expression profiling of human HNSCC.

From: Single cell deciphering of progression trajectories of the tumor ecosystem in head and neck cancer

Fig. 1: Single-cell expression profiling of human HNSCC.

A A schematic graph shows the study design. B Uniform manifold approximation and projection (UMAP) visualization of 120952 cells from 26 samples, showing 9 clusters in different colors. C Dot plots show average expression of known markers in indicated cell clusters. The dot size represents percent of cells expressing the genes in each cluster. The expression intensity of markers is shown. D UMAP visualization of 17527 cells from 3 NT samples, 16726 cells from 3 Pre samples, 14437 cells from 3 E samples, 29186 cells from 6 A samples, 10920 cells from 3 LN-in samples, 11824 cells from 2 LN-out samples, 8564 samples from 2 LN-normal samples, and 11768 cells from 4 R samples. E Proportion of 9 major cell types showed in bar plots in different sample types (left panel) and total cell number of each cell type (right panel) are shown. Source data are provided as a Source Data Fig. 1B–E.

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