Fig. 3: Evidence for shared genetic association at cis-mQTLs identified in both populations.
From: Genetic control of DNA methylation is largely shared across European and East Asian populations
a The correlation (rb) of cis-mQTL SNP effects between ancestries for 80,394 DNAm probes with significant mQTL identified in both populations. Shown are effect sizes of the lead SNPs from each ancestry and the corresponding SNP effect in other ancestry. Correlations are presented with corresponding standard errors in parentheses. b LD between lead SNPs for DNAm probes with significant mQTL identified in both populations. Shown are the r-squared values between lead SNPs calculated using the 1000 Genomes reference panel for the subset of EUR samples (79,391 SNP pairs; left) and EAS individuals (78,108 SNP pairs; right).
