Fig. 2: CUPiD performance testing in cfDNA from cohort of patients with known tumour types. | Nature Communications

Fig. 2: CUPiD performance testing in cfDNA from cohort of patients with known tumour types.

From: A cfDNA methylation-based tissue-of-origin classifier for cancers of unknown primary

Fig. 2: CUPiD performance testing in cfDNA from cohort of patients with known tumour types.

a Alluvial plot showing CUPiD performance in test cohort (170 cfDNA samples; 143 known primary tumour types, 27 NCCs). b Estimated Tumour Fraction (TF) of 143 cfDNA samples from known primary tumour types, grouped by concordance of CUPiD predictions, coloured by correct class. Dotted line denotes limit of detection of ichorCNA (3%). Boxes mark the 25th percentile (bottom), median (central bar) and 75th percentile (top); whiskers extend to 1.5 times the interquartile range. Class abbreviations are defined in Table 1. Source Data are provided as a Source Data file.

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