Fig. 2: Effects of various silicon functional groups, ligand and temperature for para C-H borylation. | Nature Communications

Fig. 2: Effects of various silicon functional groups, ligand and temperature for para C-H borylation.

From: Trialkoxysilane-Induced Iridium-Catalyzed para-Selective C–H Bond Borylation of Arenes

Fig. 2: Effects of various silicon functional groups, ligand and temperature for para C-H borylation.The alternative text for this image may have been generated using AI.

Reaction conditions: substrate 1 (0.2 mmol), B2dmg2 (1.5 equiv), [Ir(cod)(OMe)]2 (1.5 mol%), Me4phen (3.0 mol%), cyclohexane (1 mL), 100 °C, 1 h, isolated yield. Ratios of meta to para were determined from the crude 1H-NMR spectra after borylation. [a] B2pin2 used instead of B2dmg2. B2dmg2 = 4,4,4’,4’,6,6,6’,6’-Octamethyl-2,2’-bi(1,3,2-dioxaborinane). Me4phen = 3,4,7,8-Tetramethyl-1,10-phenanthroline.

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