Table 1 AUC distribution in terms of covariate usage
From: Utility of polygenic scores across diverse diseases in a hospital cohort for predictive modeling
PGS catalog | PGS calculation in the CMUH | ||||||
|---|---|---|---|---|---|---|---|
AUC ranges | Covariates included | Without covariates | Total | PGS + Age + Sex + PCs model | PGS + Age + Sex model | PGS model | Age + Sex model |
(N = 1927) | (N = 267) | (N = 2194) | (N = 457) | (N = 457) | (N = 457) | (N = 457) | |
(0.0, 0.1] | - | - | - | - | - | - | - |
(0.1, 0.2] | 0.05% | - | 0.05% | - | - | - | - |
(0.2, 0.3] | - | - | - | - | - | - | - |
(0.3, 0.4] | - | - | - | - | - | - | - |
(0.4, 0.5] | 0.05% | - | 0.05% | 1.97% | 5.25% | 3.28% | 16.63% |
(0.5, 0.6] | 24.81% | 28.52% | 25.26% | 84.25% | 83.37% | 90.15% | 78.12% |
(0.6, 0.7] | 39.11% | 50.00% | 40.43% | 10.94% | 8.53% | 5.91% | 3.50% |
(0.7, 0.8] | 24.30% | 11.11% | 22.69% | 1.31% | 1.31% | 0.44% | 0.44% |
(0.8, 0.9] | 8.92% | 8.89% | 8.91% | 1.53% | 1.53% | 0.22% | 1.31% |
(0.9, 1.0] | 2.77% | 1.48% | 2.61% | - | - | - | - |
