Fig. 1: Limited association between the gut microbiome and age in CRC patients.
From: Consistent signatures in the human gut microbiome of old- and young-onset colorectal cancer
a The number of patients in the Guangzhou cohort stratified by age and sex. b Two-dimension scatter plot shows the overall pattern of samples. Principle coordinate analysis (PCoA) was performed based on the Bray–Curtis distance calculated from the abundance profile at species level. Each point represents one sample, and color scale indicates age. Samples from female and male patients are in triangles and squares, respectively. Scatterplots of relationship between age and PCoA axis 1 (c), PCoA axis 2 (d), number of species (e), and Shannon index (f). The correlation coefficient was calculated using the Spearman method. The solid red line was fitted by smooth function in R, and the gray area is the 95% confidence interval. The Shannon index was calculated based on the abundance profile at the species level.
