Fig. 5: Expression of human transgenes in 10GE porcine kidneys. | Nature Communications

Fig. 5: Expression of human transgenes in 10GE porcine kidneys.

From: Consistent survival in consecutive cases of life-supporting porcine kidney xenotransplantation using 10GE source pigs

Fig. 5: Expression of human transgenes in 10GE porcine kidneys.

A Transgenic expression of hTBM, hEPCR, hCD47, hHO1, hCD46, and hDAFin kidney tissue as assessed by immunohistochemistry. Top panel is 10GE kidney tissue; bottom panel is wild-type kidney tissue (control). IHC staining was performed twice on each specific kidney sample. Black bar at the bottom right of each panel corresponds to 100 µm. B hTBM, hEPCR, hCD47, hHO1, hCD46 and hDAF expressed at expected molecular weight in 10GE kidney sample. WT tissue lysate acts as negative control. Actin acts as loading control for the assay. Representative data from two independent runs.

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