Fig. 3: Reduction of immune activation at 24-months.

A Significantly elevated IFN-γ and IFN-β in LC at 24-months. B Higher frequencies of activated monocytes at 3- and 8-month, but not 24-months. C Lower percentages of activated myeloid dendritic cells (mDC) at 24-months. D Higher percentages of activated plasmacytoid dendritic cells (pDC) at 3- and 8-month that decreased 24-months. Data shown as medians with interquartile ranges. LC Long COVID, MC matched controls. Mann–Whitney U test (two-sided) was used for un-paired analysis, p < 0.05 (*), < 0.01 (**) were considered significant. Data points represent n = 31 biologically independent samples per group. Source data are provided as a Source Data file.