Table 1 Weight and cardio-pulmonary exercise test performance in athletes and patients with type 2 diabetes mellitus before and after exercise interventions

From: Comparison of intramyocellular lipid metabolism in patients with diabetes and male athletes

 

Baseline difference between athletes and type 2 diabetes patients

p-value

Athletes change between baseline and deconditioning

p-value

Patients with type 2 diabetes change between baseline and exercise training

p-value

Difference in changes between athletes and type 2 diabetes patients

p-value

Weight, kg

−20 (−27 to −14)

<0.001

1.2 (0.3–2.1)

0.01

−2.6 (−3.6 to −1.6)

<0.001

3.8 (2.4–5.0)

<0.001

RER

0.005 (−0.05 to 0.06)

0.9

0.03 (−0.01 to 0.06)

0.2

−0.05 (−0.08 to −0.01)

0.01

0.07 (0.02–0.1)

0.005

VO2 peak, mL/min/kg

22 (19–24)

<0.001

−3.5 (−4.8 to −2.3)

<0.001

6.4 (5.4–7.4)

<0.001

−10 (−12 to −8)

<0.001

VO2 at AT, mL/min/kg

16 (14–18)

<0.001

−3.8 (−5.3 to −2.3)

<0.001

5.8 (4.6–7.0)

<0.001

−10 (−12 to −8)

<0.001

VO2/HR, mL/beat

6.2 (4.5–7.9)

<0.001

−2.1 (−2.7 to −1.4)

<0.001

2.7 (2.3–3.2)

<0.001

−5 (−5.5 to −4.0)

<0.001

METS

6.2 (5.6–6.9)

<0.001

−1.1 (−1.4 to −0.8)

<0.001

1.75 (1.4–2.1)

<0.001

−2.8 (−3.2 to −2.4)

<0.001

Resting Heart Rate, bpm

−7 (−13 to 1.2)

0.02

1.5 (−2.3 to 5.3)

0.4

2.1 (−1.2 to 5.4)

0.2

−0.62 (−5.6 to 4.3)

0.8

Peak Heart Rate, bpm

11 (4–19)

0.003

4.6 (1.6 to 7.7)

0.004

7.4 (2.5–12.3)

0.005

−2.8 (−8.3 to 2.8)

0.3

Resting systolic BP, mmHg

−5 (−10 to 1.0)

0.10

−3.2 (−6.9 to 0.6)

0.09

−2.0 (−6.1 to 2.3)

0.4

−1 (−6.7 to 4.2)

0.7

Resting diastolic BP, mmHg

−7.3 (−12 to −3)

0.003

1.9 (−1.2 to 5.0)

0.2

−2.8 (−5.4 to −0.17)

0.04

4.7 (1–9)

0.02

Peak systolic BP, mmHg

−2 (−10 to 7)

0.7

−8.5 (−16 to −1)

0.03

12 (6.0–17)

<0.001

−20 (−29 to −11)

<0.001

Peak diastolic BP, mmHg

−4.0 (−11 to 3)

0.3

−4.6 (−8.6 to −0.7)

0.02

−1.4 (−7 to 4)

0.6

−3 (−10 to 4)

0.34

Heart Rate recovery, bpm

3.9 (−1 to 8.8)

0.1

−1.6 (−3.6 to 0.5)

0.1

3.6 (0.5–6.6)

0.02

−5 (−8.7 to −1.5)

0.006

VE/VCO2 slope

−2.2 (−4.1 to −0.4)

0.019

−0.5 (−1.6 to 0.6)

0.4

−0.8 (−2.0 to 0.3)

0.1

0.34 (−1.2 to 1.8)

0.7

Resting O2 saturation, %

0.3 (−0.1 to 0.7)

0.1

−0.1 (−0.4 to 0.2)

0.5

0.2 (−0.25 to 0.7)

0.4

−0.30 (−0.81 to 0.204)

0.24

Peak O2 saturation, %

−0.1 (−1.4 to 1.3)

0.9

−0.5 (−1.6 to 0.6)

0.4

0.3 (−1.2 to 1.7)

0.7

−0.8 (−2.5 to 1.0)

0.4

FEV1, L

0.7 (0.3–1)

<0.001

      

Max power output, Watt

118 (96–140)

<0.001

−16 (−20 to −11)

<0.001

35 (30–41)

<0.001

−51 (−58 to −44)

<0.001

Exercise duration, seconds

86 (41–131)

<0.001

−8.6 (−26 to 9)

0.3

88 (72–104)

<0.001

−97 (−120 to −73)

<0.001

  1. Data are shown as mean and 95% confidence intervals of inter-or intra-group differences/changes parametric hypothesis tests.
  2. Athletes n = 28; type 2 diabetes patients n = 27.
  3. RER respiratory exchange ratio, VO2 oxygen consumption, AT anaerobic threshold, VO2/HR oxygen uptake per heartbeat or ‘oxygen pulse’, MET metabolic equivalents, HR heart rate, BP blood pressure, VE/VCO2 ventilatory efficiency, FEV1 forced expiratory volume in first second.