Fig. 2: Prediction-corrected visual predictive checks (n = 1000) of the final population pharmacokinetic model of primaquine (PQ) and carboxyprimaquine (CPQ) in breastfeeding women.
a Primaquine concentration in venous plasma. b Primaquine concentration in capillary plasma. c Primaquine concentration in breast milk. d Carboxyprimaquine concentration in venous plasma. e Carboxyprimaquine concentration capillary plasma. f Carboxyprimaquine concentration in breast milk. The open circles represent the observed concentrations. Solid black lines represent the median of the observations, and dashed black lines represent the 5th and 95th percentiles of the observations. The shaded areas represent the 95% confidence intervals of each simulated percentile.
