Table 1 Clinical characteristics of study participants
Discovery cohort | Validation cohort | |||||||
|---|---|---|---|---|---|---|---|---|
total | IAA | GADA | ≥2 Aab | total | IAA | GADA | ≥2 Aab | |
N, cases | 29 | 11 | 9 | 9 | 35 | 14 | 11 | 10 |
Sex (F/M) | 8/21 | 1/10 | 3/6 | 4/5 | 20/15 | 6/8 | 9/2 | 5/5 |
Age at seroconversion (SD) | 2.9 (2.0) | 2.1 (1.2) | 2.8 (1.1) | 4.1 (2.8) | 3.2 (2.7) | 2.7 (1.4) | 4.8 (3.8) | 2.1 (1.8) |
Age at T1D (SD) | 9.4 (3.3) | 8.6 (2.7) | 10 (3.4) | 9.9 (4.0) | 6.8 (4.6) | 7.6 (4.9) | 8.2 (3.4) | 4.1 (4.5) |
HLA-DR status (DR3/DR4/both) | 19/22/12 | 7/9/5 | 6/6/3 | 6/7/4 | 19/31/15 | 5/12/3 | 5/9/3 | 9/10/9 |