Table 1 Clinical characteristics of study participants

From: Distinct cellular immune responses in children en route to type 1 diabetes with different first-appearing autoantibodies

 

Discovery cohort

Validation cohort

total

IAA

GADA

≥2 Aab

total

IAA

GADA

≥2 Aab

N, cases

29

11

9

9

35

14

11

10

Sex (F/M)

8/21

1/10

3/6

4/5

20/15

6/8

9/2

5/5

Age at seroconversion (SD)

2.9 (2.0)

2.1 (1.2)

2.8 (1.1)

4.1 (2.8)

3.2 (2.7)

2.7 (1.4)

4.8 (3.8)

2.1 (1.8)

Age at T1D (SD)

9.4 (3.3)

8.6 (2.7)

10 (3.4)

9.9 (4.0)

6.8 (4.6)

7.6 (4.9)

8.2 (3.4)

4.1 (4.5)

HLA-DR status (DR3/DR4/both)

19/22/12

7/9/5

6/6/3

6/7/4

19/31/15

5/12/3

5/9/3

9/10/9

  1. N number of participants, F female, M male, SD standard deviation, T1D type 1 diabetes.