Fig. 6: Improvement in the substrate promiscuity of TS.

A Catalytic pocket of TS that contains benzoyl-CoA. B Catalytic pocket of TSF46I that contains benzoyl-CoA. C Catalytic pocket of EcCS that contains benzoyl-CoA. D Catalytic pocket of TS that contains tigloyl-CoA. E Catalytic pocket of TS that contains acetyl-CoA. F Catalytic pocket of TSF46I that contains tigloyl-CoA. G Catalytic pocket of TSF46I that contains acetyl-CoA. H Enzymatic assays of TS and TSF46I with benzoyl-CoA as the acyl donor.