Fig. 6: Mechanistic Investigations of the C–N Coupled Product Formation.
From: Decarboxylative stereoretentive C–N coupling by harnessing aminating reagent
a Computed potential energy surface of plausible rearrangements to access N-alkylamide product (unit = kcal/mol). M06-2X/6-311 + G**/SMD (solvent = DMSO, ε = 46.826)//M06-2X/6-31 G**. b Control experiment using a postulated hydroxamate intermediate.
