Fig. 1: Diet-omics SOURCE cohort demographics, sampling, and dietary and environmental exposures.
From: Diet-omics in the Study of Urban and Rural Crohn disease Evolution (SOURCE) cohort
The SOURCE cohort included 380 participants. In China, 40 newly-diagnosed Crohn disease (CD) patients and 121 healthy residents of Guangzhou (urban Ctl) and 162 healthy residents of Shaoguan district (all rural controls), a rural underdeveloped community 300 km north of Guangzhou. In Israel, 25 newly-diagnosed pre-treatment CD patients and 32 healthy controls. a Scheme (BioRender) illustrating SOURCE demographics, sampling, and metadata including exposures. b Cohort figure showing Israel and China data types and availability colored as indicated. Each row represents a subject. c Mosaic plots showing exposure rates between the different groups in China, and Israel. Full data in Supplementary Dataset 1. Two-sided *p < 0.05, **p < 0.01, ***p < 0.001, chi-square tests test. IOIBD Q International Organization of IBD questionnaire, FFQ food frequency questionnaire, MGX metagenomics, TI terminal ileum, Ctl controls.
