Fig. 6: Co-expression analysis identifies HERVs co-expressed with canonical genes and supports their role in a range of biological functions. | Nature Communications

Fig. 6: Co-expression analysis identifies HERVs co-expressed with canonical genes and supports their role in a range of biological functions.

From: Integrating human endogenous retroviruses into transcriptome-wide association studies highlights novel risk factors for major psychiatric conditions

Fig. 6: Co-expression analysis identifies HERVs co-expressed with canonical genes and supports their role in a range of biological functions.

A Proportion of HERVs and canonical genes assigned to each co-expression module, including the number of genetic features per module at the top, as detected in the European subset (N = 563 biologically independent samples). B Bubble plot showing top gene ontology (GO) term, per module. The X-axis and colour of the bubbles indicate −log10(P) (two-sided, uncorrected) of the enrichment statistic. The size of the bubbles represents the enrichment ratio. Only Bonferroni-significant GO terms are shown (Bonferroni-adjusted P < 0.05).

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