Table 3 Key genetic features of full-length plasmids in hypervirulent Klebsiella pneumoniae isolates
ID | ST | Plasmid | Inc type | Size (bp) | Virulence genes | Tra genes | T4CP | Relaxase | oriT | AMR genes | Tellurite resistance genes |
|---|---|---|---|---|---|---|---|---|---|---|---|
65 | ST23 | Helper | IncFII | 74.503 | - | TraX-D-G-H-B-Q-F-N-U-W-C-V-K-E-L-A-Y-M | + | + | + | - | - |
Phagemid | FIB | 106.291 | - | - | + | - | - | - | - | ||
75 | ST86 | Virulence | IncFIBK:HIB | 195.619 | iucABCD-iutA- iroBCDN-rmpA/A2 | - | + | - | - | - | + |
Helper | IncFII:FIA:N | 121.952 | - | TrwJ-K-M-L-N-D-E-F-G-I,TraD-A-M-L-E-K-B-V-C-W-U-N-F-Q-H-G-D-X | + | + | + | - | - | ||
78 | ST23 | Virulence | IncFIBK:HIB | 230.437 | iucABCD-iutA- iroBCDN-rmpA/A2 | - | + | - | + | - | + |
Helper | IncFII | 95.989 | - | TraM-A-L-E-K-B-V-C-W-U-N-F-Q-H-G-D-X | + | + | + | DfrA1, QnrS, SulI, TetA | - | ||
88 | ST65 | Virulence | IncFIBK:HIB | 240.534 | iucABCD-iutA- iroBCDN-rmpA/A2 | - | + | - | + | - | + |
Helper | IncA/C:N | 246.199 | - | TraM-Y-A-L-E-K-B-V-C-W-U-N-F-Q-H-G-D-X | + | + | + | AadAB, Arr2, CTX-M-15, CmlA, DfrA, LAP, OXA-10, QnrS, FloR, StrAB, SulII, TetA, VEB-1 | - | ||
121 | ST23 | Virulence | IncFIBK:HIB | 223.585 | iucABCD-iutA- iroBCDN-rmpA/A2 | - | + | - | + | - | + |
Phagemid | FIB | 109.376 | - | - | + | - | - | - | - | ||
Helper | Unknow | 176.873 | - | TraN-G-H-F-U-W-C-V-B-K | + | + | - | - | - | ||
146 | ST25 | Virulence (iuc3) | IncFIBK:FII | 241.139 | iucABCD-iutA | TraM-A-L-E-L-B-V-C-W-U-N-F-Q-H-G-D-X | + | + | + | TetA,Sul2,StrAB,DfrA14,AadA1, OXA-10,FloR,CmlA,Arr | - |
AMR | IncFIA:R | 82.512 | - | - | - | - | + | QnrS, LAP, Aac3 | - | ||
201 | ST828 | Virulence (iuc3) | IncFIBK:FII | 194.876 | iucABCD-iutA | TraX-D-G-H-B-Q-F-N-U-W-C-V-K-E-L-A-M | + | + | + | - | - |
AMR | IncFII | 82.668 | - | TrbC-A-B, TraY-X-W-U-T-R-Q-P-O-N-M-L-K-J-I-H | + | + | + | LAP, QnrS, SulII, TetA | - | ||
206 | ST25 | Virulence (iuc3) | IncFIBK:FII | 198,96 | iucABCD-iutA | TraX-I-D-G-H-B-Q-F-N-U-W-C-V-K-E-L-A-Y-M | + | + | + | TetA,QnrS,LAP-2,APH-(6),Sul2,StrAB,FloR | - |
AMR | IncFII | 77.321 | - | TraO-P-Q-R-T-U-W-X-Y, TrbC-B-A | + | + | + | SulII, DfrA, DHA, QnrS, TetA | - | ||
176 | ST1049 | Virulence | IncFIBK | 299.039 | iucABCD-iutA- iroBCDN-rmpA/A2 | - | + | - | + | - | + |
Phagemid | FIB | 111.709 | - | - | + | - | - | - | - | ||
410 | ST420 | Virulence | IncFIBK:HIB | 219.173 | iucABCD-iutA- iroBCDN-rmpA/A2 | - | + | - | + | - | + |
Phagemid | FIB | 112.412 | - | - | + | - | - | - | - |
