Fig. 2: Enantioselective carbene insertion of amide N–H bond.
From: Enantioselective synthesis of chiral amides by carbene insertion into amide N–H bond
a Difficulties in enantioselective amide N–H bond insertion reaction. b This work: Rhodium triphenylacetate and chiral squaramide co-catalyzed asymmetric amide N–H insertion.
