Fig. 5: Detection of influenza A H1N1 in clinical samples. | Nature Communications

Fig. 5: Detection of influenza A H1N1 in clinical samples.

From: Rapid and on-site wireless immunoassay of respiratory virus aerosols via hydrogel-modulated resonators

Fig. 5

a Sensor response of clinical samples from suspected positive patients (S1 ~ S4), H1N1 positive patients (P1 ~ P33), fever patients yet H1N1 negative (F1-F3), and healthy volunteers (H1 ~ H20), with qRT-PCR as reference. b Correlation of sensor response and Ct values of qRT-PCR positive samples. c Box plot of the sensor response to H1N1 positive and negative samples (n = 60). Central lines indicate the median value, box limits represent the upper and lower quartiles, and whiskers indicate 1.5 × the interquartile range above and below the upper and lower quartiles, respectively. ****P < 0.0001, two-tailed Student’s t-test. d The receiver operator characteristic (ROC) curve of the wireless immunoassay for H1N1 detection. e Comparison of the wireless immunoassay (this work) with other immuno sensors based on LFA, ELISA, EC, FET, LSPR, SPR, FL, SERS, and imaging.

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