Table 2 Descriptive statistics for chronological age, epigenetic clocks, aging pace measures, and age acceleration measures, with pearson correlation coefficients for associations with chronological age

From: Severe drought exposure in utero associates to children’s epigenetic age acceleration in a global climate change hot spot

 

Mean

SD

Maximum

Minimum

Pearson correlation coefficients with chronological age

Child chronological age (years)

6.72

1.96

9.61

1.81

1

Epigenetic clocks

     

PedBE

7.25

1.15

10.16

3.99

0.80

Wu

6.25

1.66

10.17

0.51

0.68

Horvath

8.39

2.77

15.40

2.72

0.72

Hannum

18.32

3.62

31.02

8.71

0.38

Skin & blood

4.02

1.44

8.13

0.73

0.86

PhenoAge

−3.32

6.49

17.39

−21.04

0.51

GrimAge2

32.28

3.93

48.24

23.66

0.25

DNAmTL

7.19

0.28

7.78

6.13

0.05

Aging pace measures

     

DunedinPACE

1.32

0.14

1.78

1.01

−0.35

DunedinPoAm38

1.16

0.07

1.32

0.99

0.18

Age acceleration measures

     

EAAaPedBE

0.00

0.69

1.95

−1.98

0

EAAWu

0.00

1.21

2.67

−3.39

0

EAAHorvath

0.00

1.92

5.59

−3.89

0

EAAHannum

0.00

3.35

11.50

−7.48

0

EAASkin&Blood

0.00

0.73

2.62

−2.14

0

EAAPhenoAge

0.00

0.69

1.96

−1.98

0

EAAGrimAge2

0.00

1.77

5.14

−3.58

0

EAADNAmTL

0.00

3.35

11.50

−7.48

0

  1. aEAA denotes the epigenetic age acceleration, which is calculated as the resulting residuals of regressing epigenetic clock on child’s chronological age. For example, EAAPedBE is the epigenetic age acceleration derived by taking the residuals after regressing PedBE clock on child’s chronological age. Source data are provided as a source data file.
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