Fig. 2: Substrate scope of 1 with 2a. | Nature Communications

Fig. 2: Substrate scope of 1 with 2a.

From: Para-selective nitrobenzene amination lead by C(sp2)-H/N-H oxidative cross-coupling through aminyl radical

Fig. 2

a Scope of 1,2,3,4-tetrahydroquinoline derivatives 1a. Reaction conditions A: 1 (0.5 mmol), 2a (4.0 equiv.), tBuONa (3.0 equiv.), DMSO (3.0 mL), O2 (1.0 atm) and the reaction was conducted at 40 °C. b Scope of indoline derivatives 1b. Reaction conditions B: 1 (0.5 mmol), 2a (3.0 equiv.), tBuOK (4.0 equiv.), DMF (5.0 mL), O2 (1.0 atm) and the reaction was conducted at −30 °C. c Scope of aniline derivatives 1c. d Scope of aliphatic amines 1d. Reaction conditions C: 1 (0.2 mmol), 2a (4.0 equiv.), tBuOK (3.0 equiv.), DMSO (3.0 mL), O2 (1.0 atm) and the reaction was conducted at 40 °C. e Substrates with no products. Isolated yield.

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