Fig. 3: tFUS-GC N200 modulation is conveyed through the dorsal pathway in theta and alpha frequencies.

Raincloud plots of the N200 power are presented at various frequencies and locations. The left portion of each subplot is a violin plot highlighting the distribution of the data. A box plot is at the center, marking the data median (center line), 1st and 3rd quartiles (whiskers = 1.5 * quartile ranges), and means (black triangle). The raw datapoints are presented to the right. Data are analyzed with the results of the linear mixed-effect models. EEG source imaging of V5 reveals a significant amplification of the N200 theta and alpha power for tFUS-GC modulation compared to decoupled-sham, non-modulated, and tFUS-GP control conditions. There is also significant damping of the decoupled-sham compared to the non-modulated condition. In beta and gamma frequencies, tFUS-GC exhibits amplified power compared to the non-modulated and decoupled-sham conditions, but not tFUS-GP. EEG source imaging of the superior parietal lobe shows significant N200 theta and alpha amplification in the tFUS-GC condition compared with the non-modulated, decoupled-sham, and tFUS-GP conditions. In beta and gamma frequency ranges, this amplification is only observed compared to the non-modulated. tFUS-GC is not significantly amplified compared to any of the control conditions in IT across any of the frequency ranges. One-tailed z-test key false-discovery rate adjustment: *padjusted < 0.05, **padjusted < 0.01, ***padjusted < 0.001, **** padjusted < 0.0001. Source data are provided within the Source Data file.