Fig. 2: Detectability of EV-associated HIV RNA is associated with neurocognitive deficits.
From: HIV-1 RNA in extracellular vesicles is associated with neurocognitive outcomes
The ddPCR assay measurements (n = 84) were binarized into detectable vs. non-detectable against clinical outcome and significance was tested using a two-sided Wilcoxon rank sum test for each compartment with no adjustments for multiple comparisons. The significant relationships are depicted in (a–h). a TAR vs. T-score p = 0.034, b Long LTR vs. GDS p = 0.018, c Long LTR vs. T-score p = 0.004, d Long LTR vs. Executive Functioning p = 0.001, e Long LTR vs. Attention and Working Memory p = 0.006, f Long LTR vs. Learning p = 0.011, g Long LTR vs. Memory p = 0.011, and h Tat-Rev vs. Psychomotor p = 0.018. The center represents the median, boxes represent 1st to 3rd quartile, and the whiskers represent the upper and lower fences (±1.5*IQR). CSF cerebrospinal fluid, LTR long terminal repeat. Source data are provided as a Source Data file.
