Fig. 4: Correlation between histological muscle density maps and DBSI muscle fraction maps.
From: Whole cervix imaging of collagen, muscle, and cellularity in term and preterm pregnancy
a Trichrome images of the specimens and 10× magnified views of the black-dashed-boxed regions. Specimen P1-S1 shows many longitudinal muscle fibers at middle locations radially from the canal; fiber directions indicated by yellow arrows). Specimen P1-S2 shows many circumferential muscle fibers near the cervix-uterus junction that are perpendicular (yellow⊥) to the slides. b, c Comparison of histological muscle density maps (b) and DBSI-derived muscle fraction maps (c). d Pearson correlation coefficients (two-sided, at 0.05 significance level) of DBSI muscle fiber fraction and histology muscle fiber density. Each blue dot represents the mean value from a 2.5 × 2.5 mm white grid box within the specimen’s contour in (b) and (c). Red lines are linear fits and shaded areas are 95% confidence intervals. p = 5.88 × 10−5, 2.07 × 10−25, 2.98 × 10−14, 1.85 × 10−6 from P1-S1 to NP1-S1, respectively. Source data are provided as a Source Data file.
