Fig. 5: Multi-unit activity (MUA) changes across cortical layers alongside CSD.
From: Differential cortical layer engagement during seizure initiation and spread in humans
A Example of CSD (top) and MUA (bottom) during ictal discharge generation inside the ictal onset zone (left) and the propagation pathway (right). B Example of three single laminar channels from supra-granular, granular and infra-granular layers from two participants showing both the LFP and the MUA during the whole seizure. Top, laminar electrode implanted inside the ictal onset zone. Bottom, laminar electrode implanted outside the ictal onset zone. C Normalized mean (mean values +/- SEM) CSD (purple) and MUA (black) across participants (n = 9) inside (left) and outside (right) the ictal onset zone (n = 22 seizures).
