Fig. 6: 10x Genomic single-cell transcriptome sequencing verification. | Nature Communications

Fig. 6: 10x Genomic single-cell transcriptome sequencing verification.

From: In-depth organic mass cytometry reveals differential contents of 3-hydroxybutanoic acid at the single-cell level

Fig. 6

a UMAP visualization of the single-cell sequencing results for MCF-7 cells. The three cell clusters are distinguished by different colors. b Box plot of the normalized expression levels of MT2A (upper, P = 1.18E-123) and hnRNP A1 (lower, P = 6.25E-117) among the clusters (n = 10373 cells in total). (Kruskal–Wallis test, *** denoted P < 0.001) c. Box plot of BHB relative abundance among cell populations with different expression levels of MT2A. (n = 216 cells) d. Box plot of the relative abundance of BHB among cell populations with different hnRNP A1 expression levels (n = 216 cells). All of the above boxplots show the median and the 0.25 and 0.75 quantiles, and the whiskers extend to points within the 1.5 interquartile range of the lower and upper quartiles. Source data are provided as a Source Data file for b–d.

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