Fig. 1: Global strategy for discovering AmDHs among the biodiversity. | Nature Communications

Fig. 1: Global strategy for discovering AmDHs among the biodiversity.

From: A refined picture of the native amine dehydrogenase family revealed by extensive biodiversity screening

Fig. 1

This includes five main steps: 1) environmental sampling to define the reference AmDH family (ref-AmDHs) and the NAD(P)-dependent enzyme pool, 2) sequence clustering, 3) cluster analysis including the search for distant homologs by HMM-HMM profile comparison, 4) selection of candidate enzymes and 5) production and in vitro tests of selected enzymes.

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