Table 4 Demographics and characteristics
A: Demographics and characteristics of all PD subjects in the private and public test sets | ||||
|---|---|---|---|---|
Test set | Private (n = 14) | Public (n = 26) | p-value | Test statistics |
Age (years) | 68.0 ± 7.3 [51–79] | 71.0 ± 8.1 [57–86] | 0.29 | t = −1.158 df = 38 |
Sex (% F) | 14.3 | 23.1 | 0.21 | χ2 = 1.600, df = 1 |
Disease duration (years) | 10.3 ± 6.0 [0–20] | 8.7 ± 5.2 [0–19] | 0.26 | t = 0.870, df = 38 |
MDS-UPDRS Part III on medication | 35.5 ± 7.9 [23–52] | 39.9 ± 15.2 [18–83] | 0.47 | Mann–Whitney U = 187.000 |
MDS-UPDRS Part III off medication | 47.4 ± 16.0 [30–91] | 44.0 ± 16.1 [12–90] | 0.97 | Mann–Whitney U = 127.500 |
NFOG-Q | 19.9 ± 3.7 [13–28] | 21.1 ± 3.4 [11–28] | 0.88 | t = −1.093, df = 38 |
B: Demographics and characteristics of all PD subjects in the FOG-provoking analyses, divided by their original study | |||
|---|---|---|---|
tDCS (n = 71) | DeFOG (n = 57) | Combined (n = 128) | |
Age (years) | 69.9 ± 7.8 [51–94] | 67.9 ± 7.5 [51–86] | 69.0 ± 7.7 [51–94] |
Sex (% F) | 19.7 | 31.6 | 25.2 |
Disease duration (years) | 9.2 ± 5.7 [0–23] | 12.0 ± 6.3 [1.5–30] | 10.5 ± 6.1 [0–30] |
MDS-UPDRS Part III ON medication | 37.6 ± 14.5 [15–83] | 35.0 ± 10.2 [13–56] | 36.1 ± 12.4 [13–83] |
MDS-UPDRS Part III OFF medication | 43.1 ± 16.9 [12–91] | 43.8 ± 11.7 [18–76] | 43.5 ± 14.3 [12–91] |
NFOG-Q | 19.4 ± 4.3 [6–29] | 20.4 ± 3.9 [11–28] | 19.8 ± 4.2 [6–29] |
C: Demographics and characteristics of freezer and non-freezer PD subjects with daily living, real-world data | ||||
|---|---|---|---|---|
Freezers (n = 45) | Non-freezers (n = 19) | p-value | Test statistics | |
Age (years) | 67.0 ± 7.0 [51–82] | 66.5 ± 8.0 [55–83] | 0.39 | t = 0.232, df = 63 |
Sex (% F) | 35.6 | 66.5 | 0.47 | χ2 = 0.522, df = 1 |
Disease duration (years) | 12.4 ± 6.5 [1.5–30] | 5.6 ± 5.2 [0.4–23] | 0.10 | t = 4.104, df = 63 |
MDS-UPDRS Part III ON medication | 32.7 ± 9.8 [13–56] | 26.7 ± 17.0 [5–72] | 0.09 | t = 1.788, df = 63 |
MDS-UPDRS Part III OFF medication | 42.4–12.2 [18–76] | – | – | – |
NFOG-Q | 20.1 ± 4.3 [10–28] | 0 | – | – |