Table 4 Demographics and characteristics

From: A machine learning contest enhances automated freezing of gait detection and reveals time-of-day effects

A: Demographics and characteristics of all PD subjects in the private and public test sets

Test set

Private (n = 14)

Public (n = 26)

p-value

Test statistics

Age (years)

68.0 ± 7.3 [51–79]

71.0 ± 8.1 [57–86]

0.29

t = −1.158 df = 38

Sex (% F)

14.3

23.1

0.21

χ2 = 1.600, df = 1

Disease duration (years)

10.3 ± 6.0 [0–20]

8.7 ± 5.2 [0–19]

0.26

t = 0.870, df = 38

MDS-UPDRS Part III on medication

35.5 ± 7.9 [23–52]

39.9 ± 15.2 [18–83]

0.47

Mann–Whitney U = 187.000

MDS-UPDRS Part III off medication

47.4 ± 16.0 [30–91]

44.0 ± 16.1 [12–90]

0.97

Mann–Whitney U = 127.500

NFOG-Q

19.9 ± 3.7 [13–28]

21.1 ± 3.4 [11–28]

0.88

t = −1.093, df = 38

B: Demographics and characteristics of all PD subjects in the FOG-provoking analyses, divided by their original study

 

tDCS (n = 71)

DeFOG (n = 57)

Combined (n = 128)

Age (years)

69.9 ± 7.8 [51–94]

67.9 ± 7.5 [51–86]

69.0 ± 7.7 [51–94]

Sex (% F)

19.7

31.6

25.2

Disease duration (years)

9.2 ± 5.7 [0–23]

12.0 ± 6.3 [1.5–30]

10.5 ± 6.1 [0–30]

MDS-UPDRS Part III ON medication

37.6 ± 14.5 [15–83]

35.0 ± 10.2 [13–56]

36.1 ± 12.4 [13–83]

MDS-UPDRS Part III OFF medication

43.1 ± 16.9 [12–91]

43.8 ± 11.7 [18–76]

43.5 ± 14.3 [12–91]

NFOG-Q

19.4 ± 4.3 [6–29]

20.4 ± 3.9 [11–28]

19.8 ± 4.2 [6–29]

C: Demographics and characteristics of freezer and non-freezer PD subjects with daily living, real-world data

 

Freezers (n = 45)

Non-freezers (n = 19)

p-value

Test statistics

Age (years)

67.0 ± 7.0 [51–82]

66.5 ± 8.0 [55–83]

0.39

t = 0.232, df = 63

Sex (% F)

35.6

66.5

0.47

χ2 = 0.522, df = 1

Disease duration (years)

12.4 ± 6.5 [1.5–30]

5.6 ± 5.2 [0.4–23]

0.10

t = 4.104, df = 63

MDS-UPDRS Part III ON medication

32.7 ± 9.8 [13–56]

26.7 ± 17.0 [5–72]

0.09

t = 1.788, df = 63

MDS-UPDRS Part III OFF medication

42.4–12.2 [18–76]

NFOG-Q

20.1 ± 4.3 [10–28]

0

  1. Comparisons were performed using two-tailed Student’s t-tests, Mann–Whitney U tests, and Pearson’s chi-square tests as appropriate.
  2. MDS-UPDRS Movement Disorders Society-Unified Parkinson’s Disease Rating Scale, NFOG-Q New FOG Questionnaire.