Table 3 Computed kobs of different Int3’s conversion with varying N-acyl groups

From: Electrochemical synthesis of peptide aldehydes via C‒N bond cleavage of cyclic amines

Group

Boc

Bz

Cbz

Piv

kobs/(L·mol−1·s−1)

7.2 × 10−7

8.8 × 10−4

1.8 × 10−4

8.9 × 10−2

  1. Bold formatting shows that the Piv-substituted reacts the fastest.
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