Fig. 3: Electrostatic surface potential of the cleft between two E1/E2 dimers of different alphaviruses.
From: LDL receptor in alphavirus entry: structural analysis and implications for antiviral therapy
Only two E2 subunits are shown. In VEEV and EEEV the residues forming polar bonds with LDLRAD3-D1 and VLDLR-LA1 + LA2, respectively, are indicated. Amino acids at a similar position and prominent charged residues are indicated on the other structures. The figure was created with the built-in ABPS function of ChimeraX using the PDB files mentioned above and 7KO8 (MAYV), 6IMM (SINV), and 7WC2 (GETV).
