Table 1 Optimization and control studies for transformation from trithiocarbonates to dithiocarbamates
| |||
|---|---|---|---|
No. | R = | Deviation from Standard Conditions[a] | Yield (%)[b] |
1 | -OiBu | None | 92 |
2 | -COOEt | None | <5 |
3 | -Ph | None | <5 |
4 | -CN | None | 8 |
5 | -OiBu | Reaction time: 8 h | 36 |
6 | -OiBu | Reaction time: 12 h | 74 |
7 | -OiBu | Reaction time: 36 h | 91 |
8 | -OiBu | 2 eq. TETD | 85 |
9 | -OiBu | 5 eq. TETD | 78 |
10 | -OiBu | without ZnTPP or Red Light | <5 |
11 | -OiBu | Blue Light without ZnTPP | 76 |
12 | -OiBu | AIBN at 70 °C | 65 |
13 | -OiBu | FcPF6 and DCM | 35 |
