Fig. 6: Tanimoto similarity coefficient between the mature compounds predicted from 80 MiBIG BGCs.

Seq2PKS-cyclization and Seq2PKS-basic-sugar represent versions of Seq2PKS that only consider cyclization, or cyclization plus addition of basic sugars as post-translational modifications, respectively. The similarity is obtained from Skinnider et al. Note that Seq2PKS and PRISM generate multiple structures per BGC (which are further refined using mass spectrometry data), while antiSMASH generates a single core structure (solely based on genomics data).