Fig. 8: Identification of oasomycin A BGC by Seq2PKS. | Nature Communications

Fig. 8: Identification of oasomycin A BGC by Seq2PKS.

From: Discovering type I cis-AT polyketides through computational mass spectrometry and genome mining with Seq2PKS

Fig. 8

a Domains and modules in the biosynthetic genes are identified. b Substrate specificity for each domain is predicted. c Assembly order is predicted, and the core structure is constructed by using the predicted substrates for each module. d Corresponding modifications are applied to the core structure to form hypothetical molecules. e Annotation of oasomycin A spectrum using the Dereplicator+ model. Fragments of oasomycin A matching a peak in the spectrum are shown in red (f). The annotated spectrum of oasomycin A with matched peaks is shown in red.

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