Fig. 2: Scope of secondary phosphine oxides in phosphonoiodination. | Nature Communications

Fig. 2: Scope of secondary phosphine oxides in phosphonoiodination.

From: Regio- and stereoselective access to highly substituted vinylphosphine oxides via metal-free electrophilic phosphonoiodination of alkynes

Fig. 2

Reaction conditions: 1 (0.20 mmol, 1.0 equiv), 2a or 2b (0.40 mmol, 2.0 equiv), Tf2O (0.21 mmol, 1.05 equiv), 2,6-di-tert-butylpyridine (0.40 mmol, 2.0 equiv), CHCl3 (1.0 mL), 60 °C, 3 h, then I2 (0.40 mmol, 2.0 equiv) was added for 18 h. Isolated yield and the number in parentheses is 1H NMR yield based on dimethyl terephthalate.

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