Fig. 7: Active vs. passive threat responding in males and females. | Nature Communications

Fig. 7: Active vs. passive threat responding in males and females.

From: Increased reactivity of the paraventricular nucleus of the hypothalamus and decreased threat responding in male rats following psilocin administration

Fig. 7

A Illustration depicting active vs. passive responding to the air-puff stimulus. B Males (Psilocin n = 11; Vehicle n = 12): pie chart (top) showing the proportion of active vs. passive responders at baseline. Line graph (bottom) comparing changes in the proportion of active responders in male psilocin and vehicle groups across each recording session. Each data point represents the proportion of active responders at each time period. Statistical analysis comparisons utilized a 2-sided Fisher’s exact test found significant differences between groups at baseline (p = 0.0127) and injection (p < 0.0001). C Females (Psilocin n = 12; Vehicle n = 12): pie chart (top) showing the proportion of active vs. passive responders at baseline. Line graph (bottom) comparing changes in the proportion of active responders in male psilocin and vehicle groups across each recording session. Each data point represents the proportion of active responders at each time period. Statistical analysis comparisons using a 2-sided Fisher’s exact test found significant differences between groups at baseline (p = 0.0138), injection (p < 0.0001), 2-day (p = 0.0336), and 7-day (p < 0.0001). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. BL = baseline, INJ = injection.

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