Table 1 Description of cohort outcomes and demographics

From: Data-driven prediction of continuous renal replacement therapy survival

 

UCLA CRRT

Cedars Sinai CRRT

UCLA Control

 

Overall

Do not recommend

Recommend

Overall

Do not recommend

Recommend

Do not recommend

n

 

4161

1920

2241

3263

1462

1801

1562

Outcome, n (%)

        
 

Comfort Care

1179 (28.3)

1179 (61.4)

-

984 (30.2)

984 (67.3)

-

-

 

Expired

741 (17.8)

741 (38.6)

-

478 (14.6)

478 (32.7)

-

242 (15.5)

 

Recovered renal function

602 (14.5)

-

602 (26.9)

704 (21.6)

-

704 (39.1)

-

 

Transitioned to hemodialysis

1639 (39.4)

-

1639 (73.1)

1097 (33.6)

-

1097 (60.9)

-

Total days on CRRT, median [Q1, Q3]

 

6.0 [3.0,12.0]

5.0 [2.0,12.0]

6.0 [3.0,12.0]

5.0 [3.0,10.0]

4.0 [2.0,9.0]

6.0 [4.0,11.0]

0.0 [0.0,0.0]

Year of CRRT, median [min, max]

 

2018 [2015,2021]

2018 [2015,2021]

2018 [2015,2021]

2019 [2016,2021]

2019 [2016,2021]

2019 [2016,2021]

2019 [2016,2021]

Number of previous CRRT Treatments, mean (SD)

 

0.2 (0.7)

0.1 (0.5)

0.3 (0.8)

0.2 (0.5)

0.1 (0.4)

0.2 (0.5)

0.0 (0.0)

Age, median [Q1, Q3]

 

60.0 [47.0,69.0]

60.0 [48.0,69.0]

59.0 [45.0,68.0]

66.0 [56.0,75.0]

68.0 [58.0,78.0]

63.0 [53.0,73.0]

61.0 [48.0,70.0]

Sex, n (%)

        
 

Female

1682 (40.4)

765 (39.8)

917 (40.9)

1111 (36.3)

537 (37.8)

574 (35.0)

627 (40.1)

 

Male

2479 (59.6)

1155 (60.2)

1324 (59.1)

1946 (63.7)

882 (62.2)

1064 (65.0)

935 (59.9)

Ethnicity, n (%)

        
 

Hispanic or Latino

1416 (34.0)

580 (30.2)

836 (37.3)

756 (24.7)

307 (21.6)

449 (27.4)

548 (35.1)

 

Not Hispanic or Latino

2745 (66.0)

1340 (69.8)

1405 (62.7)

2301 (75.3)

1112 (78.4)

1189 (72.6)

1014 (64.9)

Race, n (%)

        
 

American Indian or Alaska Native

15 (0.4)

11 (0.6)

4 (0.2)

4 (0.1)

1 (0.1)

3 (0.2)

30 (1.9)

 

Asian

337 (8.1)

163 (8.5)

174 (7.8)

249 (8.1)

103 (7.3)

146 (8.9)

131 (8.4)

 

Black or African American

429 (10.3)

199 (10.4)

230 (10.3)

462 (15.1)

226 (15.9)

236 (14.4)

158 (10.1)

 

Multiple Races

42 (1.0)

15 (0.8)

27 (1.2)

115 (3.8)

40 (2.8)

75 (4.6)

25 (1.6)

 

Native Hawaiian or Other Pacific Islander

21 (0.5)

10 (0.5)

11 (0.5)

12 (0.4)

3 (0.2)

9 (0.5)

9 (0.6)

 

Unknown

1268 (30.5)

555 (28.9)

713 (31.8)

500 (16.4)

287 (20.2)

213 (13.0)

591 (37.8)

 

White or Caucasian

2049 (49.2)

967 (50.4)

1082 (48.3)

1715 (56.1)

759 (53.5)

956 (58.4)

618 (39.6)

Heart comorbidities, n (%)

        
 

No

1115 (26.8)

516 (26.9)

599 (26.7)

584 (17.9)

189 (12.9)

395 (21.9)

1074 (68.8)

 

Yes

3046 (73.2)

1404 (73.1)

1642 (73.3)

2679 (82.1)

1273 (87.1)

1406 (78.1)

488 (31.2)

Liver comorbidities, n (%)

        
 

No

1159 (27.9)

532 (27.7)

627 (28.0)

1353 (41.5)

528 (36.1)

825 (45.8)

1220 (78.1)

 

Yes

3002 (72.1)

1388 (72.3)

1614 (72.0)

1910 (58.5)

934 (63.9)

976 (54.2)

342 (21.9)

Infection comorbidities, n (%)

        
 

No

1709 (41.1)

821 (42.8)

888 (39.6)

925 (28.3)

291 (19.9)

634 (35.2)

1334 (85.4)

 

Yes

2452 (58.9)

1099 (57.2)

1353 (60.4)

2338 (71.7)

1171 (80.1)

1167 (64.8)

228 (14.6)

Other comorbidities, n (%)

        
 

No

3925 (94.3)

1831 (95.4)

2094 (93.4)

3142 (96.3)

1423 (97.3)

1719 (95.4)

1315 (84.2)

 

Yes

236 (5.7)

89 (4.6)

147 (6.6)

121 (3.7)

39 (2.7)

82 (4.6)

247 (15.8)

  1. Age data was missing from 36 patients in the UCLA: CRRT cohort. Age, sex, ethnicity, and race data was missing from 206 patients in the Cedars: CRRT cohort. Note that comorbidities were identified if the CCS codes described in Section “Data Preprocessing” were recorded within 14 days before starting CRRT, which reflected the optimal window of the comprehensive model.