Table 2 Adjusted mean baseline biomarker values for groups of Black and white individuals
From: Baseline levels and longitudinal changes in plasma Aβ42/40 among Black and white individuals
Biomarker | Group | N | Mean adjusted value | Standard error | p |
|---|---|---|---|---|---|
Plasma Aβ42/Aβ40 | Black | 214 | 0.1201 | 0.0030 | |
White | 1113 | 0.1155 | 0.0030 | ||
Difference (Black–white) | 0.0046 | 0.0008 | <0.0001 | ||
Plasma Aβ42 (pg/mL) | Black | 214 | 26.25 | 2.40 | |
White | 1113 | 26.41 | 2.36 | ||
Difference (Black–white) | −0.16 | 0.61 | 0.80 | ||
Plasma Aβ40 (pg/mL) | Black | 214 | 177.8 | 22.7 | |
White | 1113 | 199.5 | 22.4 | ||
Difference (Black–white) | −21.6 | 5.7 | 0.0002 | ||
Amyloid PET Centiloid | Black | 89 | 21.6 | 13.6 | |
White | 626 | 28.2 | 13.4 | ||
Difference (Black–white) | −6.6 | 3.7 | 0.072 | ||
CSF Aβ42/40 | Black | 80 | 0.1122 | 0.0068 | |
White | 806 | 0.1069 | 0.0068 | ||
Difference (Black–white) | 0.0053 | 0.0021 | 0.014 | ||
CSF Aβ42 (pg/mL) | Black | 80 | 840 | 117 | |
White | 806 | 915 | 116 | ||
Difference (Black–white) | −75 | 37 | 0.041 | ||
CSF Aβ40 (pg/mL) | Black | 80 | 5552 | 1277 | |
White | 806 | 7284 | 1272 | ||
Difference (Black–white) | −1732 | 400 | <0.0001 | ||
CSF t-tau (pg/mL) | Black | 80 | 114.2 | 83.1 | |
White | 806 | 198.1 | 82.9 | ||
Difference (Black–white) | −84.0 | 26.1 | 0.001 | ||
CSF p-tau181 (pg/mL) | Black | 80 | 17.42 | 12.31 | |
White | 806 | 28.46 | 12.27 | ||
Difference (Black–white) | −11.04 | 3.86 | 0.004 |
