Fig. 6: Dimeric structural changes underlying the transport cycle.
From: Dimeric transport mechanism of human vitamin C transporter SVCT1
a Comparison of dimer structures of hSVCT1 and UraA between three states, in the order of putative substrate transport. Colored arrows indicate the relative movements of domains. b Schematic model for the predicted transport cycle of NAT/SLC23 members. Experimental structures are determined for the three colored states, and no structural information is currently available for the uncolored outward-open state.
