Table 1 Investigating the one-step sequential (3 + 2)/(3 + 2) cycloaddition chemistry of a nitrone-containing allene

From: One-step syntheses of diaza-dioxa-fenestranes via the sequential (3 + 2) cycloadditions of linear precursors and their structural analyses

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Entry

Base

Solvent

Temp. [°C]

Yielda [%]

1

None

Toluene

110

57

2

None

1,4-dioxane

100

75

3

None

TCE

110

89

4

Et3N

TCE

110

91

5

i-Pr2NEt

TCE

110

19

6

Pyridine

TCE

110

73

7

NaHCO3

TCE

110

77

  1. TCE 1,1,2-trichloroethane.
  2. aIsolated yield.