Fig. 4: Interactions at the α1β1 subunit interface.
From: The unique allosteric property of crocodilian haemoglobin elucidated by cryo-EM
a An overlay of deoxy HbAM and human HbA around His α1103. The carbon atoms of the α1 and β1 subunits of HbAM are shown in magenta and cyan, respectively, and those of the α1 and β1 subunits of human HbA are shown in white and salmon. b the BC corner of the α1 subunit and the H helix of the β1 subunit. The hydrogen bond formed by Arg β1135 and Ala α135 in deoxy HbAM is shown. c The α1 BC corner, β1 H helix, and the C terminus of β2 subunit of deoxy and carbonmonoxy HbAM. The carbon atoms of the α and β subunits of carbonmonoxy HbAM are shown in brown and purple, respectively. Hydrogen bonds formed by Arg β1135 are shown as dotted lines, either silver (in deoxy HbAM) or gold (in carbonmonoxy HbAM).
