Fig. 1: Schematic of hematopoietic stem and progenitor cell membrane-coated vesicles (HSPC-Lipo) production and anti-leukemic treatment.

Schematic diagram of the preparation process for Ara-C@HSPC-Lipo. The drug loaded HSPC-Lipo biomimetic vesicles were injected into leukemic mice through the tail vein and targeted to the bone marrow. Ara-C@HSPC-Lipo targeting leukemia cells through receptor-ligand mediated specific binding and delivering chemotherapy drugs to kill leukemia cells in bone marrow.