Fig. 8: Safety evaluation and analysis of HSPC-Lipo. | Nature Communications

Fig. 8: Safety evaluation and analysis of HSPC-Lipo.

From: Hematopoietic stem and progenitor cell membrane-coated vesicles for bone marrow-targeted leukaemia drug delivery

Fig. 8: Safety evaluation and analysis of HSPC-Lipo.

a Schematic illustration of animal experiment design. b Body weight of mice in different treatment groups. Data represent the mean ± s.d. (n = 6 mice). c Quantitative analysis of hematopoietic stem progenitor cells in total mononuclear cells. d Quantitative analysis of progenitor cells in total mononuclear cells. e Quantitative analysis of lineage cells in total mononuclear cells. f Quantitative analysis of absolute number of hematopoietic stem progenitor cells per legs of tibia and femur. g Quantitative analysis of absolute number of progenitor cells per legs of tibia and femur. h Quantitative analysis of absolute number of lineage cells per legs of tibia and femur. n = 6 mice (c-h). The data represent the mean ± s.d (c–h). Statistical significance of P values was calculated via a two-tailed, unpaired Student’s t test and were indicated as *P < 0.05, **P < 0.01 and ***P < 0.001. Source data are provided as a Source Data file.

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