Fig. 3: Exploring the scope of the title transformation.
From: Regioselective fluorination of allenes enabled by I(I)/I(III) catalysis
Reaction conditions: allene (0.1 mmol), catalyst (30 mol%), amine•HF (0.25 mL), DCM (0.25 mL) and Selectfluor® (0.2 mmol). Isolated yields reported. The regioselectivity was determined by 19F NMR from the crude reaction mixture. a 19F NMR yield using ethyl fluoroacetate as the internal standard. b Reaction performed on 0.20 mmol scale. c Reaction performed on 0.15 mmol scale. d DCE was used as solvent. The enantiomer of the product shown was arbitrarily shown.
