Fig. 6: Age-related differences in inferred structural weights are more common within functional brain systems.
From: A multi-modal, asymmetric, weighted, and signed description of anatomical connectivity
a Edge level correlations with age. b, c Matrices of significant results for the coarse- and fine-scale system spin tests, respectively (Cont = Control, DMN = default mode network, DAN = dorsal attention network, Lim = limbic, Sal/VAN = salience, SMN = somatomotor, TP = temporoparietal, Vis = visual). d, e Boxplots comparing the z-scores from the spin-test null model with the real values. One boxplot displays within system z-score values, and the other displays between system z-score values. Box plots, shown in red and overlaid on data points in e and f, depict the interquartile range (IQR) and the median value of the distribution. Whiskers extend to the nearest points ± 1.5 × IQR above and below the 25th and 75th percentiles. Asterisks indicate a significant difference between box plots (two-sample t-test; panel d: within N = 7, between N = 42; panel e: within N = 16, between N = 240). f Within-system z-scores from the fine-scale system spin test mapped onto cortical parcels. Panels g–i show individual edges that exhibit age-related correlations (p < 0.05; uncorrected). Blue and red edges correspond to edges whose weights decrease or increase with age, respectively. Panels g–i are presented for the sake of visualization only.
