Fig. 5: Q-Q plots of \(-{\log }_{10}\) p-value for different methods.
From: A robust cis-Mendelian randomization method with application to drug target discovery

Colors represent the five different MR methods being compared. p-values are truncated at 1 × 10−6 in this figure. The p-values are calculated based on corresponding two-sided MR tests without multiple testing adjustment. Source data are provided as a Source Data file.