Fig. 5: Feedback-driven iteration of value representation is continuously performed even in the absence of error feedback. | Nature Communications

Fig. 5: Feedback-driven iteration of value representation is continuously performed even in the absence of error feedback.

From: Anterior cingulate cortex provides the neural substrates for feedback-driven iteration of decision and value representation

Fig. 5

a Scatter plots of the mean stimulus response of each neuron in the Stable and Re-stable sessions (n = 493 cells from 5 mice). b Behavior performance of an example animal in the Stable and Re-stable sessions. c Behavior performance in T1-T3 phases in the Stable and Re-stable sessions (n = 5 mice, two-sided one-way repeated measures ANOVA with post hoc Tukey’s multiple comparisons). Mean population response to go stimulus in T1-T3 phases in the Stable session (d) and the Re-stable session (e). n  =  493 neurons from 5 mice, two-sided Friedman test with post hoc Bonferroni multiple comparisons. f The correlation of go-cue evoked population activity between the three phases in the Stable (left) and Re-stable (middle) sessions, and between those two sessions (right). g The scheme of go trials grouped by the reward outcome of the previous trial. h Average population responses to go stimulus following reward outcomes (green, post reward trials) and non-reward outcomes (red, post non-reward trials) during the Stable and Re-stable sessions, respectively. Black dots indicate the time segments when traces are different (P < 0.05, two-sided Wilcoxon rank-sum test). i Scheme of constructing GLM. j Regression coefficients of outcome history of previous trial contributing to the neural response to the go stimulus in the Stable and Re-stable session (n = 493 cells from 5 mice). The symbol * denotes a significant difference compared to 0 (two-sided one-sample Wilcoxon signed-rank test). The symbol # denotes the significant difference of coefficients of the previous trial between the Stable and Re-stable session (two-sided Wilcoxon rank-sum test). **P < 10−2, ***P < 10−3, #P < 0.05, ##P < 10−2, ###P < 10−3. Data (c, h, j) are presented as mean ± s.e.m. or (d) box plots (center line, median; box limits, upper and lower quartiles; whiskers, 1.5 × interquartile range). Statistical details are presented in Supplementary Table 1. Source data are provided as a Source data file.

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