Fig. 4: In vitro plasma stability of selected insulin analogues.
From: Enhanced disulphide bond stability contributes to the once-weekly profile of insulin icodec
Disappearance of intact insulin analogues upon incubation in human (a), dog (b) and minipig (c) plasma, n = 2. The corresponding appearance of B-chains are shown in Supplementary Fig. 5. See text for definition of insulin substitutions.
