Table 2 Multiple reaction monitoring transitions, collision energies (CE), and quantitative range (QR) for identification and quantification of doxorubicin and its metabolites
From: Kupffer cells determine intrahepatic traffic of PEGylated liposomal doxorubicin
Compound | Precursor (m/z) | Product (m/z) | CE (eV) | QR (ng/mL) |
|---|---|---|---|---|
Dox | 544.30 | 397.25 | −14 | 0.5–200 |
Doxol | 546.30 | 399.25 | −15 | 0.1–200 |
7-Deo | 399.35 | 381.25 | −20 | 0.5–50 |
Dau | 528.30 | 321.10 | −25 | Interior standard |
