Fig. 1: Background and motivation of pyridine meta-C–H functionalization. | Nature Communications

Fig. 1: Background and motivation of pyridine meta-C–H functionalization.

From: Electrochemical meta-C–H sulfonylation of pyridines with nucleophilic sulfinates

Fig. 1: Background and motivation of pyridine meta-C–H functionalization.The alternative text for this image may have been generated using AI.

a Current methods for meta-selective C–H functionalization of pyridines. b This study: Proposed electrochemical meta-C–H sulfonation of pyridine with nucleophilic sulfinates. c Representative bioactive molecules featuring meta-sulfonated pyridines. Tf triflate, Bn benzyl, DMAP dimethyl acetylenedicarboxylate, MP methyl pyruvate, SET single electron transfer.

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