Fig. 1: Schematic representation of intermediate-promoted reversible atropisomerism via heating or chemical reactions and related property changes.
From: Controlled interconversion of macrocyclic atropisomers via defined intermediates

Also shown is the production via heating of an isomer that can serve as a building block for pseudrotaxane construction or as a fullerene receptor (left). Solvent effect induced irreversible conversion between stable and metastable species of OC-4 in toluene-d8 (right).